MyBioSource.com's Rat Anti-Interleukin-17 Receptor B Antibody is a Rat monoclonal antibody. The Rat Anti-Interleukin-17 Receptor B Antibody was generated using IL17RB, and Interleukin 17 Receptor B as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Flow Cytometry.
Description
The IL17RB protein is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17A or IL17C (1, 2). This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E (3,4). The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. This antibody is recommended for applications under non-denaturing conditions